Username:
Password:
University Medical Center Groningen
Department of Genetics -
L1CAM Mutation Database
Introduction
Database
Submit data
Contact
Mutations
Protein domains
References
Reference details
Author
Year
Journal
Pages
Volume
Title
Weblink
Du et al.
1998c
Am. J. Med. Genet.
200-202
75
Somatic and germ line mosaicism and mutation origin for a mutation in the L1 gene in a family with X-linked hydrocephalus
9450886
Mutations mentioned in reference
Protein Domain
Exon/Intron
DNA Change
Protein Change
Type
Reported Classification
Details
LOVD ID
n.a.
Intron 10
c.1267+1G>A
p.?
Splice site
Disease-causing
Details
Patients
Family
# Affected relatives
DNA change
Protein change
Exon/Intron
Clinical features
Remarks
1
1
c.1267+1G>A
p.?
Intron 10
(Dys)agenesis corpus callosum, Adducted thumbs, Hydrocephalus, Mental retardation