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University Medical Center Groningen
Department of Genetics -
L1CAM Mutation Database
Introduction
Database
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Mutations
Protein domains
References
Reference details
Author
Year
Journal
Pages
Volume
Title
Weblink
Yeatman
1984
Am. J. Med. Genet.
339-344
17
Mental retardation-clasped thumb syndrome
6538754
Mutations mentioned in reference
No mutations found.
Patients
Family
# Affected relatives
DNA change
Protein change
Exon/Intron
Clinical features
Remarks
1
6
c.3531-12G>A
p.?
Intron 26
Adducted thumbs, Aphasia, Mental retardation, Spastic paraplegia
All patients: > 1 yr